Sex at tra

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These mutations have little effect on XO animals which are male already but lead to some abnormalities in XO gonadal development, indicating that tra-1 has functions in normal development of both sexes, although its major function is confined to the XX hermaphrodite. Google Scholar Articles by Hodgkin, J. All 22 transform XX animals into fertile females. Third, a high level of tra-1 activity may act to inhibit spermatogenesis in the XX germ line, thereby assisting the switch from spermatogenesis to oogenesis in the hermaphrodite. The tra-1 lf alleles are recessive and, in general, masculinizing. The results suggest that the tra-1 gene has several roles in wild-type sexual development.

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