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Putative brain structures involved in ejaculation. Sexual differentiation of the brain and behavior. Parasympathetic supply to the penis is derived from the sacral segments S2-S4 Expulsion Expulsion follows emission as the process of ejaculation climaxes, and refers to the ejection of semen through the urethral meatus. Adult and pediatric urology. Centrally, intrathecal sildenafil results in elevation of NO and cyclic guanosine monophosphate levels in MPOA causing a decreased peripheral sympathetic tone and inhibition of ejaculation The amphetamine derivative p-chloroamphetamine leads to a sudden release of 5HT in synaptic clefts triggering ejaculation in anesthetized rats with complete spinal cord lesion

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