The investigators' hypothesis is that the delivery of an immediate and substantial load of hemoglobin-associated iron from a stored unit of blood leads to changes that explain the differences in outcome between patients transfused old versus fresh blood. Please refer to this study by its ClinicalTrials. Send us your comments by March 14, Procedure: Fresh transfusion Procedure: Old transfusion. Last Update Posted : June 2, Transfusion of human volunteers with older, stored red blood cells produces extravascular hemolysis and circulating non-transferrin-bound iron.
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